The 36th International 500-Mile Sweepstakes was a motor race held at the Indianapolis Motor Speedway on Friday, May 30, 1952. It was the opening race of the 1952 AAA National Championship Trail and was also race 2 of 8 in the 1952 Formula One season.

Troy Ruttman won the race for car owner J. C. Agajanian. Ruttman, aged 22 years and 80 days, set the record for the youngest 500 winner in history. It was also the last dirt track car to win at Indy. Ruttman's win also saw him become the youngest winner of a Formula One race, a record he would hold for 51 years.

Bill Vukovich led 150 laps, but with 9 laps to go, he broke a steering linkage while leading. He nursed his car to a stop against the outside wall, preventing other cars from getting involved in the incident.

In the third year that the 500 was included in the Formula One, Ferrari entered the race with Alberto Ascari driving a Ferrari 375 Indianapolis. The effort gained considerable attention, but Ascari was forced to retire after a few laps when the hub of a wheel on his car collapsed. He was classified 31st. It was the only Formula One race in 1952 that Ascari entered and did not win.